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Larry Fox Professor Ph.D., University of Wisconsin Phone: (509) 335-0786 E-mail: fox@wsu.edu

DAIRY MANAGEMENT AND REDUCTION OF MASTITIS. Our research efforts are designed to examine new methods of control of contagious mastitis. These efforts are principally directed at control of Staphylococcus aureus and Mycoplasma sp. mastitis. Our focus is directed at the development and validation of strategies to control this disease through applied and basic research. Currently we are utilizing biotechnologies to "Fingerprint" S. aureus and Mycoplasma sp, to trace the pathogen from its reservoir to fomite to the host, the cow, for these two pathogen types. We also study the effectiveness of standard milking procedures to reduce mastitis and improve milk quality.

Specific Research Areas:

• Control of S. aureus mastitis in cows through the vaccination.
• Exotoxins in milk: affects on milk quality and mammary immunity.
• Determination of reservoirs of Mycoplasma sp. that cause mastitis.

Selected Publications:

1. Fox, L.K., C. Gradle, and A. Dee. 2006.  Disinfectant containing a complex of skin conditioners. J. Dairy Sci. 89:2539-2541.
2. Borm, A.A., L.K. Fox, K.E. Leslie, J.S. Hogan, S.M. Andrew, K.M. Moyes, S.P. Oliver, Y.H. Schukken, D.D. Hancock, C.T. Gaskins, W.E. Owens, and C. Norman.  2006.  Effects of prepartum intramammary antibiotic therapy on udder health.  J. Dairy Sci. 89:2090-2098.
3. Fox, L.K., R.N. Zadoks, and C.T. Gaskins. 2005. Biofilm production by Staphylococcus aureus associated with intramammary infection.  Vet Micro. 107:295-299.
4. Fox, L.K., J.H. Kirk, and A. Britten. 2005.  Mycoplasma mastitis: A review of transmission and control.  J. Vet. Med. 52:153-160.
5. Fox, L.K., L.Y. Oura, and C. R. Ames. 2003.  Teat Skin pH.  J. Dairy Sci.  86:3951-3952.
6. Silk, A.S., L.K. Fox, and D.D. Hancock. 2003.  Removal of hair surrounding the teat and associated bacterial counts on teat skin surface, in milk, and intramammary infections.  J. Vet. Med. B. 50:1-4.
7. Biddle, M.K., L.K. Fox, and D.D. Hancock  2003.  Patterns of mycoplasma shedding in the milk of dairy cows with intramammary mycoplasma infection. JAVMA 223:1163-1166.
8. Middleton J.R., L.K. Fox, J.M. Gay, J.W. Tyler, and T.E. Besser.  2002.  Use of pulsed-field gel electrophoresis for detecting differences in Staphylococcus aureus strain populations between dairy herds with different cattle importation practices.  Epidemiol. Infect. 129:387-395.
9. Joo, Y.S., L.K. Fox, W. Davis, G.A. Bohach, and Y.H. Park.  2001.  Staphylococcus aureus associated with mammary glands of cows:  Genotyping to distinguish different strains among herds.  Vet. Micro 80:131-138.
10. Middleton, J.R., L.K. Fox, and T.H. Smith.  2001.  Management strategies to decrease the prevalence of mastitis caused by one strain of Staphylococcus aureus in a dairy herd.  JAVMA 218:1615-1618.